Polynucleotides & Microneedling Exosomes in Harrow
The skin beneath the eyes is the thinnest on the face and the first to show fatigue, dehydration, and age. Treating it effectively requires more than topical skincare. It requires regeneration at a cellular level.
Session Time
90 minutes
Downtime
1–3 days
Results Visible
4–8 weeks
Sessions Needed
3–4 sessions
Suitable For
Fitzpatrick I–VI



The Treatment
What are Polynucleotides & Microneedling Exosomes?
Polynucleotides & Microneedling Exosomes is Medcura’s bespoke under-eye regenerative treatment, combining advanced microneedling with polynucleotides and exosomes in a single session. Polynucleotides are bio-stimulating compounds that work within the skin to stimulate tissue repair, restore hydration, and support long-term cellular renewal. Microneedling creates precise micro-channels that allow these active compounds to reach the deeper skin layers where under-eye concerns actually originate.
The exosome component amplifies the regenerative process further. Exosomes are cellular messenger particles that accelerate repair, reduce post-treatment inflammation, and support the skin’s natural healing response from within.
This protocol is exclusively designed and performed at Medcura Harrow. Every session is fully bespoke, built around your specific under-eye concerns, skin condition, and depth of treatment required.
How Medcura Treats Your Concern
Polynucleotides & Microneedling Exosomes at Medcura is a bespoke protocol combining three active components in one session, each targeting a different mechanism of under-eye concern, fully customised to your presentation.
Polynucleotides
Polynucleotides are injected into the periorbital area to stimulate collagen production and support cellular repair in the delicate under-eye skin. They address fine lines, crepey texture, and dehydration at a dermal level, working to rebuild the skin’s structural quality from within.
Microneedling
Advanced microneedling creates precise micro-channels in the under-eye skin, triggering the skin’s natural collagen induction response. This also allows the polynucleotides and exosomes to penetrate deeper into the tissue, improving their efficacy significantly compared to surface-level application alone.
Exosomes
Applied during the session, exosomes support cellular repair and accelerate the skin’s healing response in the periocular area. They reduce post-treatment inflammation, improve overall skin quality, and contribute to the brighter, more refreshed appearance that develops in the weeks following treatment.
Is This Treatment Right For You?
Polynucleotides & Microneedling Exosomes is designed for the delicate under-eye area and works best when matched to the right skin concern and skin condition. Your clinician will assess suitability at consultation before any treatment is confirmed.
Who It's Suitable For
- Fine lines, crepey texture, and surface irregularity under the eyes
- Dark circles caused by pigmentation, vascular visibility, or hollowness
- Loss of firmness and skin laxity in the periorbital area
- Chronically dehydrated or dull under-eye skin
- A persistently tired appearance that topical products have not improved
Who Should Avoid It
- Active skin infection, inflammation, or open skin in the treatment area
- Pregnant or breastfeeding
- Currently taking blood-thinning medication (increased bruising risk with microneedling)
- Active cold sores or herpes simplex around the eye area
- History of severe keloid scarring
- Any recent eye surgery: discuss timing with us at Medcura before booking
Treatment Benefits
What Your Eyes Look Like After Treatment
Polynucleotides & microneedling exosomes work progressively. Improvement develops over weeks and months as the skin rebuilds collagen, restores hydration, and responds to the regenerative compounds delivered during each session.
Smoother Texture
Crepey texture and fine lines under the eyes improve as collagen rebuilds. Many clients notice visible smoothing within four to eight weeks of their first session.
Brighter Appearance
The under-eye area appears fresher and more awake as hydration and cellular health improve. A persistently tired look that topical products cannot shift can reduce noticeably across a course of treatment.
Firmer Skin
Polynucleotides and collagen induction restore dermal support beneath the eye. Skin feels more resilient as the treatment course progresses.
Deeper Hydration
Polynucleotides restore hydration within the dermal layer itself, not just on the surface. The skin appears more plump and even in tone with each session.
Minimal Downtime
The exosome component accelerates the skin’s healing response, reducing post-session redness and swelling. Most clients return to normal activity within one to three days.
Book Your Consultation at Medcura Today
Most products designed for the under-eye area work only on the surface. Polynucleotides & Microneedling Exosomes at Medcura Harrow work at the depth where fine lines, dark circles, and crepey texture actually form, combining three regenerative components in a single bespoke session.
If your under-eye concerns have not responded to topical treatments, the issue is depth, not effort. Book your consultation at Medcura Harrow to find out what this treatment can do for your specific concerns and what a realistic course looks like for you.
Common Questions
FAQs
How long does each session take?
Each session at Medcura takes 90 minutes, including consultation, treatment, and aftercare guidance before you leave.
How many sessions will I need?
We at Medcura recommend three to four sessions, spaced four to six weeks apart, for optimal and lasting results.
Can it treat dark circles?
Yes, our treatment addresses dark circles caused by pigmentation, vascular visibility, or dehydration in the under-eye area.
Is the treatment painful?
We apply topical numbing before treatment. Most clients describe a mild sensation rather than pain during the session.
When will I see results?
Most Medcura clients notice visible improvement within four to eight weeks, with results continuing to develop across the course.